![]() This work earned JAX scientist George Snell the Nobel Prize in 1980. an in-depth understanding of the immune system’s major histocompatibility complex, making organ transplants possible.the discovery of a genetic driver for appetite that leads to diabetes and obesity (Doug Coleman) and.assisted-reproduction techniques that are used in in vitro fertilization clinics (Larry Mobraaten, John Eppig, Michael Wiles and Robert Taft).the first description of "pluripotent" cells – today known as stem cells – that can change into other specialized cells (Leroy Stevens).the first experimental bone marrow transplants that led to new treatments for blood and immunological diseases (Elizabeth Russell).the first evidence that viruses can cause cancer in mammals (C.C. ![]() the revelation that cancer is a genetic disorder, not an infectious disease, with susceptibility passed on from parents to children (C.C.Its major scientific discoveries include: The Jackson Laboratory has eight decades of experience in research and is deeply respected in the global biomedical community. Research at JAX Genomic Medicine will contribute to personalized medicine by revealing how genomic variations affect health, disease and drug response. The personalized medicine industry in the United States already generates $286 billion per year in revenues and is growing by 11 percent annually, according to PricewaterhouseCoopers. The personalized medicine revolution will yield more effective medicines with fewer adverse side effects and lead to longer, healthier lives and lower health care costs. And physicians will be able to prescribe the most effective drugs with the fewest side effects, based on the patient’s genome-driven response to those drugs. Doctors will be able to assess a person’s risk of cancer and recommend preventative measures. The Jackson Laboratory is an independent, nonprofit biomedical research institution and National Cancer Institute-designated Cancer Center based in Bar Harbor. Increasingly, disease prediction, prevention and treatment will be tailored to each patient’s unique genome, including the makeup of one's tumor or infectious microbes. One person differs from another by millions of variations in the genome, and many of these variations affect susceptibility to disease and response to treatments.Greater understanding of individual genomes is allowing scientists and clinicians to begin to "personalize" medicine. Under these conditions, JAX ® Mice strains bred by Charles River are equivalent in genetic quality to those bred by The Jackson Laboratory and provide the genetic integrity and stable phenotypes needed to support research excellence.Rapid advances in technology have made it feasible to identify a person’s unique genome. The Jackson Laboratory (Jax) was developing a center for genomic medicine, where it would develop treatments for difficult-to-treat diseases using the patient’s own genes. Since 2015 the Harold Alfond Foundation has partnered with the The Jackson Laboratory (JAX) on the Maine Cancer Genomic Initiative (MCGI). Assure genetic quality through routine use of state-of-the-art genetic quality monitoring methods such as SNP analysis.Minimise naturally occurring genetic drift by systematically re-infusing breeding colonies with pedigreed mice from The Jackson Laboratory Centerbrook, in collaboration with Tsoi/Kobus Design of Cambridge, Massachusetts, designed the 135 million Jackson Laboratory for Genomic Medicine research.One of the world’s leading distributors of human disease mouse models is The Jackson Laboratory, an independent and nonprofit biomedical research institution with. These protocols provide the following benefits: The Jackson Laboratory mice share 95 percent of the same genes as humans and have become an effective and efficient model for genetic research pertaining to human diseases. ![]() Charles River breeds JAX ® Mice in strict adherence to The Jackson Laboratory’s breeding protocols and genetic quality control guidelines. Only JAX ® Mice strains bred by Charles River in Europe are equivalent in genetic quality to those bred by The Jackson Laboratory. Through a cooperative agreement, Charles River serves as the exclusive, authorised, commercial distributor, and breeder of JAX ® Mice strains in the countries listed below: Albania
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